Toronto, Ontario
Biologics Development & Manufacturing
Toronto is our center of excellence for biologics, where process development, drug substance manufacturing, and aseptic vial filling are all seamlessly combined inside one cGMP facility.
From Process Development to Filled Vials
01
Process and Analytical Development
We develop and scale your bioprocess here, with teams that average 10+ years at the site. Analytical methods can be transferred in, or developed, qualified, and validated by our team. Master cell banks are produced on-site, and programs arriving with an established process move straight into tech transfer.
02
Drug Substance Manufacturing
Seed train and inoculum preparation feed single-use bioreactors for mammalian cell culture.
03
Purification and Conjugation
Downstream processing leverages standard and tailored chromatography, ultrafiltration, and viral reduction steps, drawing on extensive expertise across complex modalities. Our team additionally provides non-cytotoxic chemical and enzymatic conjugation services.
04
Formulation and Aseptic Vial Filling
Drug substance is formulated and filled into vials ranging from 2R to 30R sizes, then visually inspected and bulk packaged for the clinic or commercial label and pack.
05
QC Testing and Release
QC chemistry and microbiology perform IPC, release, and stability testing on-site.
06
Cold Storage and Logistics
Finished material can be held on-site or longer term at a satellite location. Resilience offers ambient and cold-chain storage options while your batch is prepared for shipment. Our facility sits in a biotech hub near Toronto Pearson International Airport, with logistics serving global markets.
Where Your Drug Product Gets Finished
Our Toronto facility supports your drug product from initial process development through clinical and commercial production. When scaling up, drug substance generated in Toronto seamlessly stays within the Resilience network, moving to our West Chester, Ohio, sites for full-scale drug product fill/finish, auto-injector assembly, specialized packaging, and global distribution, ensuring supply chain security across your program's lifecycle.
West Chester, Ohio
Formulation, aseptic fill/finish, automated visual inspection, device assembly, packaging, and in-house analytical and microbiology testing at our commercially licensed drug product facility.
Blue Ash, Ohio
Commercial packaging at our global headquarters, expanding through 2027 to add automated visual inspection, device assembly, labeling, and cold storage.
